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Article

Cytotoxic T Lymphocyte Antigen-4 Gene Variants in Type 2 Diabetic Patients with or without Neuropathy.

Iranian journal of allergy, asthma, and immunology - 1 Jun 2016

Kiani Javad, Khadempar Saedeh, Hajilooi Mehrdad, Rezaei Hamzeh, Keshavarzi Fatemeh, Solgi Ghasem

Abstract excerpt

Many studies have shown that cytotoxic T lymphocyte antigen-4 (CTLA-4) gene variants are associated with several autoimmune diseases particularly type 1 diabetes. Due to the lack of consistent data for this association with type 2 diabetes (T2D), this study explored the possible influence of CTLA-4 gene polymorphisms at -1722 (T/C), -318 (C/T), and +49 (G/A) positions for susceptibility to T2D in relation with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27424137

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Cytotoxic T Lymphocyte Antigen-4 Gene Variants in Type 2 Diabetic Patients with or without Neuropathy.PMID 27424137Read ↗

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The promoter region of the CTLA4 gene is associated with type 1 diabetes mellitus.Semantic proximity Read ↗

Association between the CTLA-4 +49A/G polymorphism and type 1 diabetes: a meta-analysis.Semantic proximity Read ↗

The CTLA-4 gene region of chromosome 2q33 is linked to, and associated with, type 1 diabetes. Belgian Diabetes Registry.Semantic proximity Read ↗

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