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Article

White matter changes and the development of motor phenotypes in de novo Parkinson's Disease.

Journal of the neurological sciences - 15 Aug 2016

Moccia Marcello, Tedeschi Enrico, Ugga Lorenzo, Erro Roberto, Picillo Marina, Caranci Ferdinando, Barone Paolo, Brunetti Arturo

Abstract excerpt

BACKGROUND: Parkinson's Disease (PD) patients are usually divided into Tremor Dominant (TD) and Postural Instability/Gait Difficulty (PIGD) subtypes. The latter is characterized by axial motor symptoms and worse outcomes, possibly also because of comorbid white matter disease. Therefore, the current study investigated the importance of Age-Related White Matter Changes (ARWMCs) in the development of different PD...

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Source

Identifiers

PMID: 27423590
DOI: 10.1016/j.jns.2016.06.015

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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