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Article

Cortical Implications of Advancing Age and Disease Duration in Parkinson's Disease Patients with Postural Instability and Gait Dysfunction.

Journal of Parkinson's disease - 5 May 2016

Herb Joshua N, Rane Swati, Isaacs David A, Van Wouwe Nelleke, Roman Olivia C, Landman Bennett A, Dawant Benoit M, Hedera Peter, Zald David H, Neimat Joseph S, Wylie Scott A, Donahue Manus J, Claassen Daniel O

Abstract excerpt

BACKGROUND: Parkinson's Disease patients with predominant gait dysfunction appear to have reduced cortical thickness compared to other motor phenotypes. The extent to which advancing age or disease duration impact the pattern of these distinctions is unclear. OBJECTIVE: We examine if PD patients with predominant signs of postural instability and gait dysfunction are distinguished by distinct patterns of cerebral...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27164041
DOI: 10.3233/JPD-150753
PMCID: PMC5826542

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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