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Association of Gyrification Pattern, White Matter Changes, and Phenotypic Profile in Patients With Parkinson Disease.

Neurology - 11 May 2021

Tang Xie, Zhang Yuanchao, Liu Daihong, Hu Yixin, Jiang Liling, Zhang Jiuquan

Abstract excerpt

OBJECTIVE: To investigate the cortical gyrification changes as well as their relationships with white matter (WM) microstructural abnormalities in the akinetic-rigid (AR) and tremor-dominant (TD) subtypes of Parkinson disease (PD). METHODS: Sixty-four patients with the AR subtype, 26 patients with the TD subtype, and 56 healthy controls (HCs) were included in this study. High-resolution T1-weighted and...

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PMID: 33766988
DOI: 10.1212/WNL.0000000000011894

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