Article
Mapping liver fat female-dependent quantitative trait loci in collaborative cross mice.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Dec 2016
Atamni Hanifa J Abu-Toamih, Botzman Maya, Mott Richard, Gat-Viks Irit, Iraqi Fuad A
Abstract excerpt
Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease in the western world, with spectrum from simple steatosis to non-alcoholic steatohepatitis, which can progress to cirrhosis. NAFLD developments are known to be affected by host genetic background. Herein we emphasize the power of collaborative cross (CC) mouse for dissecting this complex trait and revealing quantitative...
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