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Article

Loss of Transcription Factor CREBH Accelerates Diet-Induced Atherosclerosis in Ldlr-/- Mice.

Arteriosclerosis, thrombosis, and vascular biology - 1 Sept 2016

Park Jong-Gil, Xu Xu, Cho Sungyun, Lee Ann-Hwee

Abstract excerpt

OBJECTIVE: Liver-enriched transcription factor cAMP-responsive element-binding protein H (CREBH) regulates plasma triglyceride clearance by inducing lipoprotein lipase cofactors, such as apolipoprotein A-IV (apoA-IV), apoA-V, and apoC-II. CREBH also regulates apoA-I transcription. This study aims to determine whether CREBH has a role in lipoprotein metabolism and development of atherosclerosis. APPROACH AND...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diet, High-Fat

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Share to Lipoproteins, VLDL

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Source

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Identifiers

PMID: 27417587
DOI: 10.1161/ATVBAHA.116.307790
PMCID: PMC5722211

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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