Article
Increased variability in Apc(Min)/+ intestinal tissue can be measured with microultrasound.
Scientific reports - 13 Jul 2016
Fatehullah A, Sharma S, Newton I P, Langlands A J, Lay H, Nelson S A, McMahon R K, McIlvenny N, Appleton P L, Cochran S, Näthke I S
Abstract excerpt
Altered tissue structure is a feature of many disease states and is usually measured by microscopic methods, limiting analysis to small areas. Means to rapidly and quantitatively measure the structure and organisation of large tissue areas would represent a major advance not just for research but also in the clinic. Here, changes in tissue organisation that result from heterozygosity in Apc, a precancerous...
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