Article
Cholinergic genetics of visual attention: Human and mouse choline transporter capacity variants influence distractibility.
Journal of physiology, Paris - 1 Sept 2016
Sarter Martin, Lustig Cindy, Blakely Randy D, Koshy Cherian Ajeesh
Abstract excerpt
The basal forebrain cholinergic projection system to the cortex mediates essential aspects of visual attention performance, including the detection of cues and the response to performance challenges (top-down control of attention). Higher levels of top-down control are mediated via elevated levels of cholinergic neuromodulation. The neuronal choline transporter (CHT) strongly influences the synthesis and release...
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