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Article

Nicotinic receptor gene CHRNA4 interacts with processing load in attention.

PloS one - 22 Dec 2010

Espeseth Thomas, Sneve Markus Handal, Rootwelt Helge, Laeng Bruno

Abstract excerpt

BACKGROUND: Pharmacological studies suggest that cholinergic neurotransmission mediates increases in attentional effort in response to high processing load during attention demanding tasks [1]. METHODOLOGY/PRINCIPAL FINDINGS: In the present study we tested whether individual variation in CHRNA4, a gene coding for a subcomponent in α4β2 nicotinic receptors in the human brain, interacted with processing load in...

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Source

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Identifiers

PMID: 21203548
DOI: 10.1371/journal.pone.0014407
PMCID: PMC3008676

Genes

CHRNA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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