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Article

Interactive effects of APOE and CHRNA4 on attention and white matter volume in healthy middle-aged and older adults.

Cognitive, affective & behavioral neuroscience - 1 Mar 2006

Espeseth Thomas, Greenwood Pamela M, Reinvang Ivar, Fjell Anders M, Walhovd Kristine B, Westlye Lars T, Wehling Eike, Lundervold Astri, Rootwelt Helge, Parasuraman Raja

Abstract excerpt

In the present study, we investigated age-related changes in interactions between efficiency of neuronal repair mechanisms and efficiency of cholinergic neurotransmission in the context of attentional orienting. In addition, we explored white matter volume changes as possible neuronal underpinnings. A sample of 230 healthy middle-aged (53-64 years) and older (65-75 years) adults was genotyped for polymorphisms of...

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Share to Apolipoprotein E4
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Pattern Recognition, Visual

Share to Photic Stimulation

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Share to Receptors, Nicotinic

Source

Identifiers

PMID: 16869227
DOI: 10.3758/cabn.6.1.31

Genes

APOE
CHRNA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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