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Mutations in Human Interferon α2b Gene and Potential as Risk Factor Associated with Female Breast Cancer.

Cancer biotherapy & radiopharmaceuticals - 1 Aug 2016

Ahmed Fayyaz, Mahmood Nasir, Shahid Saman, Hussain Zahid, Ahmed Ishtiaq, Jalal Amir, Ijaz Bushra, Shahid Abubaker, Mujtaba Ghulam, Mustafa Tanveer

Abstract excerpt

The current study explored the potential links between breast cancer and human interferon α-2b (hIFNα-2b) gene mutations. The hIFNα-2b gene was amplified from breast cancer tumor tissue samples (N = 60) by polymerase chain reaction (PCR) and the products were subjected to gene sequencing. A total of 38 (63.3%) samples showed positive PCR amplification results. Several of these also exhibited frequent alterations...

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Identifiers

PMID: 27403569
DOI: 10.1089/cbr.2016.2046

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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