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Mutations of the human interferon alpha-2b gene in brain tumor patients exposed to different environmental conditions.

Cancer gene therapy - 1 May 2015

Shahid S, Nawaz Chaudhry M, Mahmood N, Sheikh S

Abstract excerpt

This study was aimed at finding out mutations of an anticancerous, antiviral and immunomodulatory gene (human interferon alpha-2b) in low- and high-grade brain tumor patients and correlate from hematological profiles. A molecular analysis was performed in which DNAs were extracted from brain biopsy samples of brain tumor patients. The gene was amplified through the PCR technique, and genetic data from sequencing...

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PMID: 25837663
DOI: 10.1038/cgt.2015.12

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