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EXPRESSION AND EFFECTS OF MUTANT Bombyx mori ACETYLCHOLINESTRASE1 IN BmN CELLS.

Archives of insect biochemistry and physiology - 1 Oct 2016

Wang Bin-Bin, Xie Yi, Li Fan-Chi, Ni Min, Xu Kai-Zun, Tian Jiang-Hai, Hu Jing-Sheng, Xue Bin, Shen Wei-De, Li Bing

Abstract excerpt

The main mechanism of toxicity of organophosphate (OP) and carbamate (CB) insecticides is their irreversible binding and inhibition of acetylcholinestrase (AChE), encoded by ace1 (acetylcholinestrase gene 1), leading to eventual death of insects. Mutations in AChE may significantly reduce insects susceptibility to these pesticides. Bombyx mori is an important beneficial insect, and no OP- or CB-resistant strains...

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PMID: 27402326
DOI: 10.1002/arch.21345

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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