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Metabolic detoxification and ace-1 target site mutations associated with acetamiprid resistance in Aedes aegypti L

30 Aug 2022

Abstract excerpt

Despite the continuous use of chemical interventions, Aedes-borne diseases remain on the rise. Neonicotinoids are new, safer, and relatively effective pharmacological interventions against mosquitoes. Neonicotinoids interact with the postsynaptic nicotinic acetylcholine receptors (nAChRs) of the insect central nervous system, but the absence of nAChR polymorphism in resistant phenotypes makes their involvement in...

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PMID: 36111159
DOI: 10.3389/fphys.2022.988907

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