Article
Portal Venous Blood Circulation Supports Immunosuppressive Environment and Pancreatic Cancer Circulating Tumor Cell Activation.
Pancreas - 1 Jan 2017
Arnoletti Juan Pablo, Zhu Xiang, Almodovar Alvin J O, Veldhuis Paula P, Sause Ryan, Griffith Elizabeth, Corpus George, Chang Jeffrey C C, Fanaian Naʼim, Litherland Sally A
Abstract excerpt
OBJECTIVES: Aggressive spread and liver metastases are predominant features of pancreatic ductal adenocarcinoma (PDAC). This study investigates activation of PDAC circulating tumor cells (CTC) and immunosuppression in the portal venous system. METHODS: Portal venous and peripheral blood were collected during pancreaticoduodenectomy from patients with PDAC (n = 21) or other non-PDAC pancreatic conditions (n = 20)....
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