Article
The Variants in the 3' Untranslated Region of the Matrix Metalloproteinase 9 Gene as Modulators of Treatment Outcome in Children with Asthma.
Lung - 1 Jun 2018
Dragicevic Sandra, Kosnik Mitja, Divac Rankov Aleksandra, Rijavec Matija, Milosevic Katarina, Korosec Peter, Skerbinjek Kavalar Maja, Nikolic Aleksandra
Abstract excerpt
PURPOSE: The maintaining of asthma control is difficult due to high variability in response to therapy among patients. Since matrix metalloproteinase 9 (MMP9) is implicated in inflammation and remodeling of asthmatic airways, it could be associated with adequate response to asthma therapy. The aim of this study was to investigate whether variants in 3' end of the MMP9 gene are associated with clinical phenotype...
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