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Article

DNA sequence variations of metalloproteinases: their role in asthma and COPD.

Postgraduate medical journal - 1 Apr 2007

Sampsonas Fotis, Kaparianos Alexander, Lykouras Dimosthenis, Karkoulias Kiriakos, Spiropoulos Kostas

Abstract excerpt

Asthma and chronic obstructive pulmonary disease (COPD) are complex genetic diseases that cause considerable morbidity and mortality worldwide. Genetic variability interacting with environmental and ethnic factors is presumed to cause tobacco smoke susceptibility and to influence asthma severity. A disintegrin and metalloproteinase 33 (ADAM33) and matrix metalloproteinase-9 (MMP9) appear to have important roles...

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Source

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Identifiers

PMID: 17403951
DOI: 10.1136/pgmj.2006.052100
PMCID: PMC2600023

Genes

ADAM33
MMP9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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