Impacts of Matrix Metalloproteinase-9 Promoter Genotypes on Asthma Risk.

doi:10.21873/invivo.13677

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Article

Impacts of Matrix Metalloproteinase-9 Promoter Genotypes on Asthma Risk.

In vivo (Athens, Greece) - 1 Jan 2000

Chiu Kuo-Liang, He Jie-Long, Chen Guan-Liang, Shen Te-Chun, Chen Li-Hsiou, Chen Jaw-Chyun, Tsai Chia-Wen, Chang Wen-Shin, Hsia Te-Chun, Bau DA-Tian

Abstract excerpt

BACKGROUND/AIM: The overexpression of matrix metalloproteinase-9 (MMP9) has been observed in asthmatic patients, yet the role of MMP9 genotype in determining asthma susceptibility remains unresolved. This study aimed to elucidate the contribution of MMP9 promoter rs3918242 genotype to asthma risk in Taiwan. MATERIALS AND METHODS: A cohort comprising 453 non-asthmatic healthy controls and 198 asthmatic cases was...

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PMID: 39187355
DOI: 10.21873/invivo.13677
PMCID: PMC11363755

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