Association of GRIN2B gene polymorphism and Obsessive Compulsive disorder and symptom dimensions: A pilot study.

doi:10.1016/j.psychres.2016.06.027

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Article

Association of GRIN2B gene polymorphism and Obsessive Compulsive disorder and symptom dimensions: A pilot study.

Psychiatry research - 30 Sept 2016

Kohlrausch Fabiana Barzotti, Giori Isabele Gomes, Melo-Felippe Fernanda Brito, Vieira-Fonseca Tamiris, Velarde Luis Guillermo Coca, de Salles Andrade Juliana Braga, Fontenelle Leonardo Franklin

Abstract excerpt

The etiology of OCD is largely unknown, but neuroimaging and pharmacological studies suggest that glutamatergic system plays a significant role on OCD development. We genotyped one polymorphism at GRIN2B (rs1019385) by real time Polymerase Chain Reaction in a sample of Brazilian Obsessive-Compulsive patients and healthy controls, and evaluated its influence on OCD. We found the T-allele and TT genotype to be...

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PMID: 27394963
DOI: 10.1016/j.psychres.2016.06.027

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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