Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mode localization in the cooperative dynamics of protein recognition.

The Journal of chemical physics - 7 Jul 2016

Copperman J, Guenza M G

Abstract excerpt

The biological function of proteins is encoded in their structure and expressed through the mediation of their dynamics. This paper presents a study on the correlation between local fluctuations, binding, and biological function for two sample proteins, starting from the Langevin Equation for Protein Dynamics (LE4PD). The LE4PD is a microscopic and residue-specific coarse-grained approach to protein dynamics,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to HIV Protease
Share to Insulin-Like Growth Factor II
Share to Molecular Dynamics Simulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to Nuclear Magnetic Resonance, Biomolecular

Share to Protein Binding

Share to Protein Conformation

Share to Receptor, IGF Type 2

Source

Identifiers

PMID: 27394125
DOI: 10.1063/1.4954506

Genes

IGF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mode localization in the cooperative dynamics of protein recognition.PMID 27394125Read ↗

Interplay between partner and ligand facilitates the folding and binding of an intrinsically disordered protein.Semantic proximity Read ↗

Exploring the Dynamics of Four RNA-Dependent RNA Polymerases by a Coarse-Grained ModelSemantic proximity Read ↗

Small molecule binding to disordered proteinsSemantic proximity Read ↗

Domain communication in the dynamical structure of human immunodeficiency virus 1 protease.Semantic proximity Read ↗

Integrating Structural Information to Study the Dynamics of Protein-Protein Interactions in Cells.Semantic proximity Read ↗

Dynamical network of residue-residue contacts reveals coupled allosteric effects in recognition, catalysis, and mutation.Semantic proximity Read ↗

A Disordered Loop Mediates Heterogeneous Unfolding of an Ordered Protein by Altering the Native Ensemble.Semantic proximity Read ↗

Elements and modulation of functional dynamics.Semantic proximity Read ↗

Computational screening of the effects of mutations on protein-protein off-rates and dissociation mechanisms by τRAMDSemantic proximity Read ↗

Characterization of folding mechanisms of Trp-cage and WW-domain by network analysis of simulations with a hybrid-resolution model.Semantic proximity Read ↗

Precise Generation of Conformational Ensembles for Intrinsically Disordered Proteins via Fine-tuned Diffusion ModelsSemantic proximity Read ↗

Computational screening of the effects of mutations on protein-protein off-rates and dissociation mechanisms by τRAMD.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.