Article
Association of HLA-DP/DQ and STAT4 polymorphisms with ankylosing spondylitis in Southwest China.
International immunopharmacology - 1 Oct 2016
Liu Xinle, Yang Bin, Li Lixin, Cai Bei, Liao Yun, Li Linhui, Wu Zhiqiang, Wang Lanlan
Abstract excerpt
Ankylosing spondylitis (AS) is a highly heritable complex inflammatory arthritis disease. Genetic factors are thought to be crucial in the pathogenesis of AS. However, few data are available on the relationship between HLA-DP/DQ and STAT4 polymorphisms and AS susceptibility in the Chinese population. Therefore, we examined HLA-DP/DQ and STAT4 polymorphisms (rs3077, rs9277535, rs7453920 and rs7574865) in a total...
Read the complete abstract on PubMed