Article
Heritability of in vitro phenotypes exhibited by murine adipose-derived stromal cells.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Oct 2016
Jiang Zixuan, Harrison David E, Parsons Makayla E, McClatchy Susan, Jacobs Lawrence, Pazdro Robert
Abstract excerpt
Adipose-derived stromal cells (ADSCs) exhibit significant potential as therapeutic agents to promote tissue regeneration. Success of ADSC-based therapies is dependent upon efficient cell expansion in vitro as well as postinjection survival in the caustic milieu of damaged tissue. Genetic background regulates ADSC proliferative capacity and stress resistance, but the extent of the genetic effect size is not...
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