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Physioxia improves the selectivity of hematopoietic stem cell expansion cultures

21 Feb 2023

Abstract excerpt

Hematopoietic stem cells (HSCs) are a rare type of hematopoietic cell that can entirely reconstitute the blood and immune system after transplantation. Allogeneic HSC transplantation (HSCT) is used clinically as a curative therapy for a range of hematolymphoid diseases; however, it remains a high-risk therapy because of its potential side effects, including poor graft function and graft-versus-host disease...

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PMID: 36809781
DOI: 10.1182/bloodadvances.2023009668

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