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Article

Molecular aspects of β, β-carotene-9', 10'-oxygenase 2 in carotenoid metabolism and diseases.

Experimental biology and medicine (Maywood, N.J.) - 1 Nov 2016

Wu Lei, Guo Xin, Wang Weiqun, Medeiros Denis M, Clarke Stephen L, Lucas Edralin A, Smith Brenda J, Lin Dingbo

Abstract excerpt

Carotenoids, the carotenes and xanthophylls, are essential components in human nutrition. β, β-carotene-9', 10'-oxygenase 2 (BCO2), also named as β, β-carotene-9', 10'-dioxygenase 2 (BCDO2) catalyzes the asymmetrical cleavage of carotenoids, whereas β, β-carotene-15, 15'-monooxygenase (BCMO1) conducts the symmetrical cleavage of pro-vitamin A carotenoids into retinoid. Unlike BCMO1, BCO2 has a broader substrate...

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Identifiers

PMID: 27390265
DOI: 10.1177/1535370216657900
PMCID: PMC5068469

Genes

BCO2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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