Article
Vitamin A formation in animals: molecular identification and functional characterization of carotene cleaving enzymes.
The Journal of nutrition - 1 Jan 2004
von Lintig Johannes, Vogt Klaus
Abstract excerpt
Vitamin A and its derivatives (retinoids) are essential components in vision; they contribute to pattern formation during development and exert multiple effects on cell differentiation. It has been known for 70 y that the key step in vitamin A biosynthesis is the oxidative cleavage of a carotenoid with provitamin A activity. While a detailed biochemical characterization of the respective enzymes could be achieved...
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