Article
Effects of Heavy Drinking on T-Cell Phenotypes Consistent with Immunosenescence in Untreated HIV Infection.
Alcoholism, clinical and experimental research - 1 Aug 2016
So-Armah Kaku A, Edelman E Jennifer, Cheng Debbie M, Doyle Margaret F, Patts Gregory J, Gnatienko Natalia, Krupitsky Evgeny M, Samet Jeffrey H, Freiberg Matthew S
Abstract excerpt
BACKGROUND: The role of alcohol consumption in HIV-related adaptive immune dysfunction is debated. We hypothesized that heavy drinking would be associated with greater evidence of immunosenescence (i.e., aging-related decline of adaptive immune function) among antiretroviral therapy (ART)-naïve HIV-infected individuals. METHODS: Using data from the Russia ARCH cohort study, we conducted a cross-sectional analysis...
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