Article
Chronic Alcohol Exposure Among People Living with HIV Is Associated with Innate Immune Activation and Alterations in Monocyte Phenotype and Plasma Cytokine Profile.
Frontiers in immunology - 1 Jan 2022
Underwood Michelle L, Park Byung, Uebelhoer Luke S, Gu Geoffrey, Kunkel Lynn E, Korthuis Philip T, Cook Ryan R, Sekaly Rafick Pierre, Ribeiro Susan Pereira, Lancioni Christina L
Abstract excerpt
Despite advances in antiretroviral therapy, chronic immune activation continues to be observed among individuals with well-controlled HIV viral loads, and is associated with non-AIDS defining morbidities among people living with HIV. Alcohol use disorder impacts a significant proportion of individuals living with HIV, and alcohol exposure is known to damage the intestinal epithelium which may increase...
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