Article
The role of pharmacogenetics in the treatment of chronic hepatitis C infection.
Pharmacotherapy - 1 Feb 2014
Kawaguchi-Suzuki Marina, Frye Reginald F
Abstract excerpt
Hepatitis C virus (HCV) chronically infects 170 million people worldwide. Until recently, combination therapy with peginterferon-α (pegIFN) and ribavirin (RBV) has been the standard of care. However, for many patients, especially those infected with the most common HCV genotype 1 (HCV-1), this treatment has resulted in unsatisfactory treatment response rates. Many clinical factors, including pharmacogenetics,...
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