Article
Low-dose pegylated interferon-α2a plus ribavirin therapy for elderly and/or cirrhotic patients with HCV genotype-1b and high viral load.
Antiviral therapy - 1 Jan 2014
Tamai Hideyuki, Mori Yoshiyuki, Shingaki Naoki, Kawashima Akira, Tsukuda Hiroshi, Higashi Katsuhiko, Moribata Kosaku, Kawaguchi Masanori, Ueda Kazuki, Deguchi Hisanobu, Inoue Izumi, Maekita Takao, Iguchi Mikitaka, Kato Jun, Ichinose Masao
Abstract excerpt
BACKGROUND: Pegylated interferon (PEG-IFN) plus ribavirin therapy is still recommended for elderly and/or cirrhotic patients. This study examined whether sustained virological response (SVR) to low-dose PEG-IFN-α2a plus ribavirin therapy for elderly and/or cirrhotic patients could be predicted based on viral reduction within 2 weeks after therapy initiation or interleukin IL-(28B) polymorphism and viral...
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