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Article

Producing infectious enterovirus type 71 in a rapid strategy

4 Jun 2010

Abstract excerpt

BACKGROUND: Enterovirus 71 (EV71) is an etiologic agent of hand-foot-and-mouth disease (HFMD), and recent HFMD epidemics worldwide have been associated with a severe form of brainstem encephalitis associated with pulmonary edema and high case-fatality rates. EV71 contains a positive-sense single-stranded genome RNA of approximately 7400 bp in length which encodes a polyprotein with a single open reading frame...

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PMID: 20525351
DOI: 10.1186/1743-422x-7-116

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