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Article

DNA vaccine constructs against enterovirus 71 elicit immune response in mice

19 Apr 2007

Abstract excerpt

BACKGROUND: Enterovirus 71 (EV71) is a major causative viral agent responsible for large outbreaks of hand, foot and mouth disease (HFMD), a common rash illness in children and infants. There is no effective antiviral treatment for severe EV71 infections and no vaccine is available. The objectives of this study were to design and construct a DNA vaccine against Enterovirus 71 using the viral capsid protein (VP1)...

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PMID: 17445254
DOI: 10.1186/1479-0556-5-6

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