Article
Preliminary Application of Precision Genomic Medicine Detecting Gene Variation in Patients with Multifocal Osteosarcoma.
Orthopaedic surgery - 1 May 2016
Zhang Hao-Qiang, Li Ming-Hui, Gao Peng, Lan Ping-Heng, Fan Bo, Xiao Xin, Lu Ya-Jie, Chen Guo-Jing, Wang Zhen
Abstract excerpt
OBJECTIVES: The purpose of this study was to present our clinical experience of treating multifocal osteosarcoma (MFOS) in our center and gain more insight into the biology of this rare condition; in particular, to address with the help of precision genomic medicine the issue of whether the multiple osteosarcoma (OS) lesions in such patients are multi-centric or originate from one primary lesion and metastasize...
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