Article
Androgen receptor as potential therapeutic target in metastatic endometrial cancer.
Oncotarget - 2 Aug 2016
Tangen Ingvild Løberg, Onyango Therese Bredholt, Kopperud Reidun, Berg Anna, Halle Mari K, Øyan Anne M, Werner Henrica M J, Trovik Jone, Kalland Karl Henning, Salvesen Helga B, Krakstad Camilla
Abstract excerpt
PURPOSE: The expression and involvement of estrogen (ER) and progesterone receptor (PR) is extensively studied in endometrial cancer. Androgen receptor (AR) is a hormone receptor less studied in female cancers, and we here aim to investigate the expression level of AR in endometrial cancer precursor lesions, primary tumors and metastases, and its potential as therapeutic target. RESULTS: Expression of AR was...
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