Article
Electrostatic effects on the folding stability of FKBP12.
Protein engineering, design & selection : PEDS - 1 Aug 2016
Batra Jyotica, Tjong Harianto, Zhou Huan-Xiang
Abstract excerpt
The roles of electrostatic interactions in protein folding stability have been a matter of debate, largely due to the complexity in the theoretical treatment of these interactions. We have developed computational methods for calculating electrostatic effects on protein folding stability. To rigorously test and further refine these methods, here we carried out experimental studies into electrostatic effects on the...
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