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Article

Uncovering specific electrostatic interactions in the denatured states of proteins.

Biophysical journal - 4 Aug 2010

Shen Jana K

Abstract excerpt

The stability and folding of proteins are modulated by energetically significant interactions in the denatured state that is in equilibrium with the native state. These interactions remain largely invisible to current experimental techniques, however, due to the sparse population and conformational heterogeneity of the denatured-state ensemble under folding conditions. Molecular dynamics simulations using...

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Identifiers

PMID: 20682271
DOI: 10.1016/j.bpj.2010.05.009
PMCID: PMC2913194

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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