Cribriform neuroepithelial tumor: molecular characterization of a SMARCB1-deficient non-rhabdoid tumor with favorable long-term outcome.

doi:10.1111/bpa.12413

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Article

Cribriform neuroepithelial tumor: molecular characterization of a SMARCB1-deficient non-rhabdoid tumor with favorable long-term outcome.

Brain pathology (Zurich, Switzerland) - 1 Jul 2017

Johann Pascal D, Hovestadt Volker, Thomas Christian, Jeibmann Astrid, Heß Katharina, Bens Susanne, Oyen Florian, Hawkins Cynthia, Pierson Christopher R, Aldape Kenneth, Kim Sang-Pyo, Widing Eva, Sumerauer David, Hauser Péter, van Landeghem Frank, Ryzhova Marina, Korshunov Andrey, Capper David, Jones David T W, Pfister Stefan M, Schneppenheim Reinhard, Siebert Reiner, Paulus Werner, Frühwald Michael C, Kool Marcel, Hasselblatt Martin

Abstract excerpt

Rhabdoid phenotype and loss of SMARCB1 expression in a brain tumor are characteristic features of atypical teratoid/rhabdoid tumors (ATRT). Rare non-rhabdoid brain tumors showing cribriform growth pattern and SMARCB1 loss have been designated cribriform neuroepithelial tumor (CRINET). Small case series suggest that CRINETs may have a relatively favorable prognosis. However, the long-term outcome is unclear and it...

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Identifiers

PMID: 27380723
DOI: 10.1111/bpa.12413
PMCID: PMC8028967

Genes

SMARCB1
TYR
MYC
SHH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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