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Article

Gene duplication and divergence produce divergent MHC genotypes without disassortative mating.

Molecular ecology - 1 Sept 2016

Dearborn Donald C, Gager Andrea B, McArthur Andrew G, Gilmour Morgan E, Mandzhukova Elena, Mauck Robert A

Abstract excerpt

Genes of the major histocompatibility complex (MHC) exhibit heterozygote advantage in immune defence, which in turn can select for MHC-disassortative mate choice. However, many species lack this expected pattern of MHC-disassortative mating. A possible explanation lies in evolutionary processes following gene duplication: if two duplicated MHC genes become functionally diverged from each other, offspring will...

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Identifiers

PMID: 27376487
DOI: 10.1111/mec.13747
PMCID: PMC5021581

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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