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Article

Non-neutral evolution and reciprocal monophyly of two expressed Mhc class II B genes in Leach's storm-petrel.

Immunogenetics - 1 Feb 2015

Dearborn Donald C, Gager Andrea B, Gilmour Morgan E, McArthur Andrew G, Hinerfeld Douglas A, Mauck Robert A

Abstract excerpt

The major histocompatibility complex (Mhc) is subject to pathogen-mediated balancing selection and can link natural selection with mate choice. We characterized two Mhc class II B loci in Leach's storm-petrel, Oceanodroma leucorhoa, focusing on exon 2 which encodes the portion of the protein that binds pathogen peptides. We amplified and sequenced exon 2 with locus-specific nested PCR and Illumina MiSeq using...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 25416539
DOI: 10.1007/s00251-014-0813-2

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