Article
Intronic primers reveal unexpectedly high major histocompatibility complex diversity in Antarctic fur seals.
Scientific reports - 26 Oct 2022
Tebbe Jonas, Ottensmann Meinolf, Havenstein Katja, Efstratiou Artemis, Lenz Tobias L, Caspers Barbara A, Forcada Jaume, Tiedemann Ralph, Hoffman Joseph I
Abstract excerpt
The major histocompatibility complex (MHC) is a group of genes comprising one of the most important components of the vertebrate immune system. Consequently, there has been much interest in characterising MHC variation and its relationship with fitness in a variety of species. Due to the exceptional polymorphism of MHC genes, careful PCR primer design is crucial for capturing all of the allelic variation present...
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