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Article

CYP2C19 loss-of-function alleles are not associated with clinical outcome of clopidogrel therapy in patients treated with newer-generation drug-eluting stents.

Medicine - 1 Jun 2016

Choi Ik Jun, Koh Yoon-Seok, Park Mahn-Won, Her Sung Ho, Choi Yun-Seok, Park Chul-Soo, Park Hun-Jun, Kim Pum-Joon, Chung Wook-Sung, Kim Ho-Sook, Shin Jae-Gook, Seung Ki-Bae, Chang Kiyuk

Abstract excerpt

CYP2C19 loss-of-function (LOF) alleles adversely affect clinical outcome of clopidogrel therapy. Recent introduction of a newer-generation drug-eluting stent (DES) has significantly reduced the occurrence of stent thrombosis.The aim of this study was to evaluate the impact of CYP2C19 LOF alleles on clinical outcome in patients treated with the newer-generation DES.The effects of CYP2C19 genotypes were evaluated...

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Identifiers

PMID: 27368038
DOI: 10.1097/MD.0000000000004049
PMCID: PMC4937952

Genes

DES

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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