Article
CYP2C19 phenotype, stent thrombosis, myocardial infarction, and mortality in patients with coronary stent placement in a Chinese population.
PloS one - 1 Jan 2013
Xie Xiang, Ma Yi-Tong, Yang Yi-Ning, Li Xiao-Mei, Ma Xiang, Fu Zhen-Yan, Zheng Ying-Ying, Chen Bang-Dang, Liu Fen
Abstract excerpt
BACKGROUND: Several studies have indicated that CYP2C19 loss-of-function polymorphisms have a higher risk of stent thrombosis (ST) after percutaneous coronary interventions (PCIs). However, this association has not been investigated thoroughly in a Chinese population. In this study, we aimed to determine the effect of CYP2C19*2 and CYP2C19*3 loss-of-function polymorphisms on the occurrence of ST and other adverse...
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