Article
Benchmarking of methods for identification of antimicrobial resistance genes in bacterial whole genome data.
The Journal of antimicrobial chemotherapy - 1 Sept 2016
Clausen Philip T L C, Zankari Ea, Aarestrup Frank M, Lund Ole
Abstract excerpt
OBJECTIVES: Next generation sequencing (NGS) may be an alternative to phenotypic susceptibility testing for surveillance and clinical diagnosis. However, current bioinformatics methods may be associated with false positives and negatives. In this study, a novel mapping method was developed and benchmarked to two different methods in current use for identification of antibiotic resistance genes in bacterial WGS...
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