Article
Genotyping using whole-genome sequencing is a realistic alternative to surveillance based on phenotypic antimicrobial susceptibility testing.
The Journal of antimicrobial chemotherapy - 1 Apr 2013
Zankari Ea, Hasman Henrik, Kaas Rolf Sommer, Seyfarth Anne Mette, Agersø Yvonne, Lund Ole, Larsen Mette Voldby, Aarestrup Frank M
Abstract excerpt
OBJECTIVES: Antimicrobial susceptibility testing of bacterial isolates is essential for clinical diagnosis, to detect emerging problems and to guide empirical treatment. Current phenotypic procedures are sometimes associated with mistakes and may require further genetic testing. Whole-genome sequencing (WGS) may soon be within reach even for routine surveillance and clinical diagnostics. The aim of this study was...
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