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Article

Large-scale assessment of antimicrobial resistance marker databases for genetic phenotype prediction: a systematic review.

The Journal of antimicrobial chemotherapy - 1 Nov 2020

Mahfouz Norhan, Ferreira Inês, Beisken Stephan, von Haeseler Arndt, Posch Andreas E

Abstract excerpt

BACKGROUND: Antimicrobial resistance (AMR) is a rising health threat with 10 million annual casualties estimated by 2050. Appropriate treatment of infectious diseases with the right antibiotics reduces the spread of antibiotic resistance. Today, clinical practice relies on molecular and PCR techniques for pathogen identification and culture-based antibiotic susceptibility testing (AST). Recently, WGS has started...

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PMID: 32658975
DOI: 10.1093/jac/dkaa257
PMCID: PMC7566382

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