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Article

The effect of APOE genotype on the delivery of DHA to cerebrospinal fluid in Alzheimer's disease.

Alzheimer's research & therapy - 30 Jun 2016

Yassine Hussein N, Rawat Varun, Mack Wendy J, Quinn Joseph F, Yurko-Mauro Karin, Bailey-Hall Eileen, Aisen Paul S, Chui Helena C, Schneider Lon S

Abstract excerpt

BACKGROUND: Apolipoprotein E (APOE) ɛ4 and low cerebrospinal fluid (CSF) amyloid-β42 (Aβ42) levels are predictors for developing Alzheimer's disease (AD). The results of several studies indicate an interaction between docosahexaenoic acid (DHA) consumption and cognitive outcomes by APOE genotype. Our objective in the present study was to examine whether APOE ɛ4 genotype and low CSF Aβ42 levels were associated...

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Source

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Identifiers

PMID: 27358067
DOI: 10.1186/s13195-016-0194-x
PMCID: PMC4928349

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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