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Article

The Calreticulin gene and myeloproliferative neoplasms.

Journal of clinical pathology - 1 Oct 2016

Clinton Aoibhinn, McMullin Mary Frances

Abstract excerpt

The Philadelphia negative myeloproliferative neoplasms include polycythaemia vera (PV), essential thrombocytopenia (ET) and primary myelofibrosis (PMF). Patients with these conditions were mainly thought to harbour JAK2V617F mutations or an Myeloproliferative leukaemia (MPL) substitution. In 2013, two revolutionary studies identified recurrent mutations in a gene that encodes the protein calreticulin (CALR). This...

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Source

Identifiers

PMID: 27354406
DOI: 10.1136/jclinpath-2016-203899

Genes

CALR
MPL
JAK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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