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Article

ppGpp regulation of RpoS degradation via anti-adaptor protein IraP.

Proceedings of the National Academy of Sciences of the United States of America - 31 Jul 2007

Bougdour Alexandre, Gottesman Susan

Abstract excerpt

IraP is a small protein that interferes with the delivery of sigma(S) (RpoS) to the ClpXP protease by blocking the action of RssB, an adaptor protein for sigma(S) degradation. IraP was previously shown to mediate stabilization of sigma(S) during phosphate starvation. Here, we show that iraP is transcribed in response to phosphate starvation; this response is mediated by ppGpp. The iraP promoter is positively...

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Identifiers

PMID: 17640895
DOI: 10.1073/pnas.0705561104
PMCID: PMC1937563

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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