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Article

Homooligomerization of ABCA3 and its functional significance.

International journal of molecular medicine - 1 Aug 2016

Frixel Sabrina, Lotz-Havla Amelie S, Kern Sunčana, Kaltenborn Eva, Wittmann Thomas, Gersting Søren W, Muntau Ania C, Zarbock Ralf, Griese Matthias

Abstract excerpt

ABCA3 is a surfactant lipid transporter in the limiting membrane of lamellar bodies in alveolar type II cells. Mutations in the ATP-binding cassette, sub-family A (ABC1), member 3 (ABCA3) gene cause respiratory distress syndrome in newborns, and chronic interstitial lung disease in children and adults. ABCA3 belongs to the class of full ABC transporters, which are supposed to be functional in their monomeric...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27352740
DOI: 10.3892/ijmm.2016.2650

Genes

ABCA3
ABCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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