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Article

The Contemporary Approach to CALR-Positive Myeloproliferative Neoplasms.

International journal of molecular sciences - 25 Mar 2021

Belčič Mikič Tanja, Pajič Tadej, Zver Samo, Sever Matjaž

Abstract excerpt

CALR mutations are a revolutionary discovery and represent an important hallmark of myeloproliferative neoplasms (MPN), especially essential thrombocythemia and primary myelofibrosis. To date, several CALR mutations were identified, with only frameshift mutations linked to the diseased phenotype. It is of diagnostic and prognostic importance to properly define the type of CALR mutation and subclassify it...

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Identifiers

PMID: 33806036
DOI: 10.3390/ijms22073371
PMCID: PMC8038093

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Related research

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The Contemporary Approach to CALR-Positive Myeloproliferative Neoplasms.PMID 33806036Read ↗

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False-negative CALR mutation in a suspected myeloproliferative neoplasm: identification, resolution and corrective action.Semantic proximity Read ↗

[Research Progress on CALR Mutation in the Myeloproliterative Neoplasm -Review].Semantic proximity Read ↗

CALR, JAK2, and MPL mutation profiles in patients with four different subtypes of myeloproliferative neoplasms: primary myelofibrosis, essential thrombocythemia, polycythemia vera, and myeloproliferative neoplasm, unclassifiable.Semantic proximity Read ↗

CALR mutations in a cohort of JAK2 V617F negative patients with suspected myeloproliferative neoplasms.Semantic proximity Read ↗

An overview on CALR and CSF3R mutations and a proposal for revision of WHO diagnostic criteria for myeloproliferative neoplasms.Semantic proximity Read ↗

Carlituculin and JAK2 Exon 12 Mutation Screening in Patients with Myeloproliferative Neoplasm’s in Jeddah Region, Saudi ArabiaSemantic proximity Read ↗

Clinicopathological differences exist between CALR- and JAK2-mutated myeloproliferative neoplasms despite a similar molecular landscape: data from targeted next-generation sequencing in the diagnostic laboratory.Semantic proximity Read ↗

JAK2, CALR, and MPL Mutation Profiles in Colombian patients with BCR-ABL Negative Myeloproliferative Neoplasms.Semantic proximity Read ↗

CALR mutation profile in Irish patients with myeloproliferative neoplasms.Semantic proximity Read ↗

A rare CALR variant mutation and efficient peginterferon alfa-2a response in a patient with essential thrombocythemia.Semantic proximity Read ↗

Molecular testing for JAK2, MPL, and CALR in myeloproliferative neoplasms.Semantic proximity Read ↗

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