Article
Bayesian logistic regression in detection of gene-steroid interaction for cancer at PDLIM5 locus.
Journal of genetics - 1 Jun 2016
Wang Ke-Sheng, Owusu Daniel, Pan Yue, Xie Changchun
Abstract excerpt
The PDZ and LIM domain 5 (PDLIM5) gene may play a role in cancer, bipolar disorder, major depression, alcohol dependence and schizophrenia; however, little is known about the interaction effect of steroid and PDLIM5 gene on cancer. This study examined 47 single-nucleotide polymorphisms (SNPs) within the PDLIM5 gene in the Marshfield sample with 716 cancer patients (any diagnosed cancer, excluding minor skin...
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